Transthyretin Amyloidosis and Social Security Disability
Amyloidosis is a disease that develops when substances that are called amyloid proteins build up in your organs. Amyloid proteins are abnormal proteins that are usually made by cells in your bone marrow. Amyloid proteins can take place in any organ or tissue in your body.
Amyloidosis is a disease that may involve different organs in different people. The reason for this is because there are many different kinds of amyloid proteins.
Amyloidosis often includes different organs and systems in your body. Organs and systems that are affected by amyloidosis may include your spleen, liver, heart, kidneys, gastrointestinal tract and nervous system.
There are different types of amyloidosis. The kind of small fibers (protein fibrils) that are deposited in your tissues and organs are what distinguishes each of the kinds of amyloidosis. Some of the different types of amyloidosis are secondary amyloidosis, amyloid - primary, senile amyloidosis and familial (inherited) amyloidosis.
In addition to the systemic kinds of amyloidosis that have just been mentioned, amyloid deposits can also be localized in a specific part of your body. Localized amyloidosis can be associated with adult onset diabetes, endocrine tumors, normal aging and Alzheimer’s disease.
Transthyretin is a normal blood protein. Its purpose is to take thyroid hormone and vitamin A to your body’s tissues where they are necessary for normal metabolism.
Transthyretin amyloidosis is a type of amyloidosis that is caused by mutations (defects) that take place in the transthyretin protein. Most of the time, transthyretin amyloidosis affects your peripheral nervous system. However, this disease may also affect your autonomic nervous system and, in some instances, your central nervous system (spinal cord and brain).
There are three primary kinds of transthyretin amyloidosis
They are the neuropathic type, the cardiac type and the leptomeningeal type. These three forms of transthyretin amyloidosis are identified by the systems of your body that they affect and the signs and symptoms that they produce.
Signs you may have Transthyretin Amyloidosis
The neuropathic form of transthyretin amyloidosis mainly involves your autonomic and peripheral nervous systems, which leads to problems with controlling your bodily functions and peripheral neuropathy. Possible signs and symptoms with this neuropathic form may include:
- Difficulty urinating
- Orthostatic hypotension (a sharp drop in your blood pressure when you stand up)
- Sexual impotence
- Various eye difficulties
- Carpal tunnel syndrome that is marked by tingling, weakness and numbness in your fingers and hands
- Kidney and heart problems
The cardiac kind of transthyretin amyloidosis is evidenced by heart problems. Possible signs and symptoms of cardiac form are:
- Orthostatic hypertension (a rise in your blood pressure when you assume an upright position)
- Arrhythmia (an abnormal heartbeat)
- Cardiomegaly (an enlarged heart)
- Occasionally, in some instances, mild peripheral neuropathy
The leptomeningeal form of transthyretin amyloidosis mainly affects your central nervous system (your brain and spinal cord). Possible signs and symptoms may include:
- Ataxia (problems with coordinating your movements)
- Dementia (loss of intellectual function)
- Spastic paralysis (weakness and stiffness in your muscles)
- Hydrocephalus (a build up of fluid in your brain)
- Bleeding and stroke in your brain.
Are you incapacitated and unable to work as a result of transthyretin amyloidosis and/or complications that have been brought about by this disease. Have you filed for Social Security disability benefits or disability benefits from the Social Security Administration because of your disability?
Did the Social Security Administration turn down your request for disability benefits? If so, you may still be able to get the financial assistance that you are in need of. Disabilitycasereview.com can help you in working with the Social Security Administration.
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