Antiphospholipid Antibody Syndrome and Getting Disability
Antiphospholipid antibody syndrome is a disorder that is marked by blood coagulation. This blood coagulation leads to blood clots (thrombosis) occurring in both your arteries and veins.
Pregnancy-related complications can also take place. These include things like miscarriage, severe preeclampsia or preterm delivery.
Antiphospholipid antibody syndrome develops from the autoimmune production of antibodies against phospholipid (aPL). This is one of your cell membrane substances. In particular, antiphospholipid antibody syndrome is marked by antibodies that are formed against cardiolipin (anti-cardiolipin antibodies) and β2 glycoprotein I.
Primary antiphospholipid antibody syndrome is the medical term that is used when this syndrome takes place independently of any other related disorder or disease. This syndrome is referred to as secondary antiphospholipid antibody syndrome when it occurs in conjunction with other autoimmune diseases, such as lupus.
The Rare Catastrophic Antiphospholipid Antibody Syndrome
In rare instances, antiphospholipid antibody syndrome may lead to rapid organ failure that results from generalized blood clots. There is a high risk of death in these instances. This is known as "catastrophic antiphospholipid antibody syndrome".
There are estimates that anywhere from 1 to 5% of the general population has antiphospholipid antibody syndrome in the United States. This syndrome is a large concern for women as 75 to 90% of the people who have antiphospholipid antibody syndrome are women.
Miscarriages and Antiphospholipid antibody syndrome
Antiphospholipid antibody syndrome is the thing that accounts for 10 to 25% of miscarriages that recur. This syndrome is responsible for one third of all strokes that take place in people who are under the age of 50. Antiphospholipid antibody syndrome also accounts for 15 to 20% of all of the cases of deep vein thrombosis (blood clots in large veins).
Factors of developing antiphospholipid antibodies
At this time, the cause of primary antiphospholipid antibody syndrome is not known. However, there are some factors that are associated with developing antiphospholipid antibodies. Some of these are:
- Genetic predispositions
- Certain medications
The Cause of secondary antiphospholipid antibody syndrome
The cause of secondary antiphospholipid antibody syndrome is thought to be lupus or some other autoimmune ailment. An autoimmune disorder is one where your immune system that normally attacks anything foreign that invades your body, for some unknown reason, attacks the healthy tissues and cells of your own body.
Symptoms and Signs
The signs and symptoms that you have with antiphospholipid antibody syndrome usually depend on where blood clots develop in your body or where they move to in your body. Possible signs and symptoms that you may experience include:
- Stillbirths or miscarriages that recur, as well as other complications of pregnancy
- Deep vein thrombosis (blood clots that occur in your legs)
- Pulmonary embolism (blood clots that move to your lungs)
- A stroke
There are also signs and symptoms that you may experience that are not as common. Some of these are:
- The occurrence of neurological signs and symptoms, such as dementia, headaches and seizures
- Cognitive difficulties, such as poor memory
- Mental health problems that may include psychosis or depression
- Movement disorder that is marked by your limbs and body jerking uncontrollably (chorea)
- A sudden hearing loss
- Episodes of bleeding, primarily from your gums and nose
- A red rash that has a lacy, net-like pattern on your knees and wrists (livedo reticularis)
- Cardiovascular disease, particularly heart valve difficulties
Have you become incapacitated and unable to work because of complications that have occurred as a result of antiphospholipid antibody syndrome or other disorders that you have in addition to this disorder. If this is the case, are you in need of financial assistance?
Have you sought after Social Security disability benefits or disability benefits from the Social Security Administration? Was your attempt denied by the Social Security Administration? Get a free disability evaluation now!
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